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INVOLVEMENT OF EOSINOPHILS IN ACUTE MYELOID-LEUKEMIA WITH MONOSOMY-7 DEMONSTRATED BY FLUORESCENCE IN-SITU HYBRIDIZATION

被引：17
|
作者：
KWONG, YL [1 ]
CHAN, LC [1 ]
机构：
[1] UNIV HONG KONG,QUEEN MARY HOSP,DEPT PATHOL,HONG KONG,HONG KONG
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 1994年 / 88卷 / 02期
关键词：
AML; MONOSOMY; 7; EOSINOPHILS; FISH;
D O I：
10.1111/j.1365-2141.1994.tb05035.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Monosomy 7 is the commonest monosomy in acute myeloid leukaemia (AML). A patient with AML and monosomy 7 was investigated by fluorescence in situ hybridization. Monosomy 7 could be demonstrated in the blasts and also in mature eosinophils, but apparently not in lymphocytes. Monosomy 7 may occur in a multipotential myeloid progenitor cell as part of the multi-step leukaemogenic process.
引用
收藏
页码：389 / 391
页数：3
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