IN-VIVO MODEL FOR ADVANCED BLADDER-CARCINOMA

被引：0
|
作者：
OTTO, T
GOEPEL, M
REMBRINK, K
RUBBEN, H
机构：
来源：
AKTUELLE UROLOGIE | 1995年 / 26卷
关键词：
LOCALLY ADVANCED BLADDER CARCINOMA; CHEMICAL CARCINOGENESIS;
D O I：
10.1055/s-2008-1057868
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
In an experimental model or chemical induced bladder carcinoma in mice (strain B6D2F1) we used beta-hydroxybutylnitrosamine as carcinogen. We found that tumor progression cannot be prevented by intraperitoneal application of interferon alpha 2b (3 x 10(5) IU) in comparison to a control group which was treated by phosphate buffered saline (PBS) only. 11/27 mice in the control group and 10/27 animals in the interferon group developed advanced carcinoma.
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页码：81 / 83
页数：3
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