GENETICS OF CANCER PREDISPOSITION AND PROGRESSION

被引：0
|
作者：
SCHWECHHEIMER, K
CAVENEE, WK
机构：
[1] LUDWIG INST CANC RES,SAN DIEGO,CA
[2] UNIV CALIF SAN DIEGO,DEPT MED,LA JOLLA,CA 92093
[3] UNIV CALIF SAN DIEGO,CTR MOLEC GENET,LA JOLLA,CA 92093
来源：
CLINICAL INVESTIGATOR | 1993年 / 71卷 / 06期
关键词：
MOLECULAR GENETICS; CANCER PREDISPOSITION; CANCER PROGRESSION; ONCOGENES; TUMOR SUPPRESSOR GENES;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The development of human cancer is a multistep process that entails a progressively more malignant phenotype through the evolution of cellular subsets with increasing numbers of genetic alterations. Here we review the molecular genetics of human cancer predisposition and progression and describe paradigmatic cancer types and cancer syndromes. We also briefly consider the future impact of molecular biology on cancer diagnosis and treatment.
引用
收藏
页码：488 / 502
页数：15
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