Update on the use of direct oral anticoagulants for the prevention and treatment of thromboembolism

被引:0
|
作者
Jacobs, Anna [1 ,2 ]
Kabra, Rajesh [3 ]
Das, Pranab [4 ]
Oliphant, Carrie S. [1 ,2 ]
机构
[1] Methodist Univ Hosp, Dept Pharm, 1265 Union Ave, Memphis, TN 38104 USA
[2] Univ Tennessee, Coll Pharm, Dept Clin Pharm, 920 Madison Ave, Memphis, TN 38163 USA
[3] Univ Tennessee, Hlth Sci Ctr, Div Cardiol, 1325 Eastmoreland Ave Suite 460, Memphis, TN 38104 USA
[4] St Francis Cardiol Associates, 6005 Pk Ave,Suite500 B, Memphis, TN 38119 USA
关键词
apixaban; atrial fibrillation; betrixaban; dabigatran; edoxaban; review; rivaroxaban; venous thromboembolism;
D O I
10.2217/fca-2017-0045
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Following publication of our review article 4 years ago, there has been an uptake in the use of nonvitamin K oral antagonists, also known as direct oral anticoagulants. The most recent Xa inhibitors to receive approval are edoxaban, which has been approved for use in both atrial fibrillation and venous thromboembolism prevention and betrixaban, which has been approved in the USA for extended thromboprophylaxis in the medically ill population. Additional analyses of certain types of atrial fibrillation patients have now become available. Ongoing prescriber vigilance is recommended as additional information continues to emerge with this class of medications. The purpose of this paper is to provide an update on the use of the direct oral anticoagulant agents for the prevention and treatment of thromboembolism.
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页码:89 / 99
页数:11
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