A DISCRIMINANT FUNCTION-ANALYSIS OF VARIOUS INTERFERON PARAMETERS AMONG ALCOHOLICS AND HEAVY SMOKERS

被引：10
|
作者：
WINDLE, M
MONDUL, T
WHITNEY, RB
CUMMINGS, KM
STADLER, I
CHADHA, KC
机构：
[1] ROSWELL PK CANC INST ELM & CARLTON ST,BUFFALO,NY 14263
[2] RES INST ALCOHOLISM,BUFFALO,NY 14203
来源：
DRUG AND ALCOHOL DEPENDENCE | 1993年 / 31卷 / 02期
关键词：
ALCOHOL; TOBACCO; IMMUNOSUPPRESSIVE; INTERFERONS; NATURAL KILLER;
D O I：
10.1016/0376-8716(93)90066-Y
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
A three-group design of alcoholics, heavy smokers and controls was used to investigate the status of the interferon system, including natural killer cell activity. Group differences were indicated via discriminant function analysis which correctly classified 86% of subjects. Test-retest relations were investigated for 14 subjects following a 30-day alcoholic inpatient program. Whereas significant immune suppression was indicated at the time of detoxification, recovery was evident at the 30-day follow-up. Results are discussed in terms of the significance of alcohol abuse on immune system functioning with consequences for susceptibility to viruses, bacteria and medical illnesses.
引用
收藏
页码：139 / 147
页数：9
相关论文
共 50 条
12345