A STUDY RELATING TO BIOAVAILABILITY AND RENAL ELIMINATION OF BISMUTH AFTER ORAL-ADMINISTRATION OF BASIC BISMUTH NITRATE

被引：0
|
作者：
BEHRENDT, WA
GROGER, C
KUHN, D
SCHULZ, HU
TOPFMEIER, P
机构：
[1] MED UNIV LUBECK,ANGIOL & GERIATR KLIN,FUNKT SEINHEIT KLIN PHARMAKOL,RATZEBURGER ALLEE 160,W-2400 LUBECK 1,GERMANY
[2] TEMMLER PHARMA GMBH,MARBURG,GERMANY
[3] LAB PROF DR SCHMIDT GAYLE DR LIMBACH,DR WALCH,HEIDELBERG,GERMANY
来源：
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS | 1991年 / 29卷 / 09期
关键词：
BISMUTH; BLOOD CONCENTRATION; ENTERAL ABSORPTION; RENAL EXCRETION;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The extent to which bismuth is absorbed following single and multiple oral administration of basic bismuth nitrate was investigated in healthy male subjects. The blood concentration of bismuth and the amounts excreted in urine and feces were determined. The results show that only a small fraction of the administered bismuth dose given in this form is absorbed. Existing differences in the absorption kinetics between this relatively insoluble bismuth salt and colloidal bismuth citrate are discussed.
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页码：357 / 360
页数：4
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