Effectiveness and safety of nicotine replacement therapy: A systematic review

Nicotine replacement therapy (NRT) is the use of various forms of nicotine delivery methods intended to replace the nicotine obtained from smoking or other tobacco usage. This reduces the withdrawal symptoms associated with smoking cessation and helps resist the urge to smoke cigarettes. The aim of this review is to determine the effectiveness of the different forms of NRT (chewing gum, transdermal patches, nasal spray, inhalers, and tablets) in achieving asceticism from cigarettes. As a method of delivering nicotine into the bloodstream, NRT is thought to be a comparatively less-dangerous method than tobacco smoking.