QUANTIFICATION OF TIAPROFENIC ACID USING VOLTAMMETRIC AND SPECTROPHOTOMETRIC TECHNIQUES

被引:9
|
作者
ALI, AMM [1 ]
EMARA, KM [1 ]
KHODARI, M [1 ]
机构
[1] UNIV ASSIUT,FAC PHARM,DEPT PHARMACEUT ANALYT CHEM,ASSIUT,EGYPT
关键词
TIAPROFENIC ACID DETERMINATION; POLAROGRAPHIC STUDY; CYCLIC VOLTAMMETRY; DIRECT CURRENT STRIPPING VOLTAMMETRY; SPECTROPHOTOMETRY;
D O I
10.1039/an9941901071
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Two methods for the determination of tiaprofenic acid (Surgam) are described. Direct current polarography and cyclic voltammetry were used to study the reduction behaviour of tiaprofenic acid, whereas direct current stripping voltammetry was applied to the quantitative measurement of the drug in dosage form and in biological media. The spectrophotometric method depends on the determination of the drug after extraction as an ion-association complex with Safranine-T in chloroform at pH 7.4.
引用
收藏
页码:1071 / 1074
页数:4
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