TIAPROFENIC ACID DETERMINATION;
POLAROGRAPHIC STUDY;
CYCLIC VOLTAMMETRY;
DIRECT CURRENT STRIPPING VOLTAMMETRY;
SPECTROPHOTOMETRY;
D O I:
10.1039/an9941901071
中图分类号:
O65 [分析化学];
学科分类号:
070302 ;
081704 ;
摘要:
Two methods for the determination of tiaprofenic acid (Surgam) are described. Direct current polarography and cyclic voltammetry were used to study the reduction behaviour of tiaprofenic acid, whereas direct current stripping voltammetry was applied to the quantitative measurement of the drug in dosage form and in biological media. The spectrophotometric method depends on the determination of the drug after extraction as an ion-association complex with Safranine-T in chloroform at pH 7.4.