Pharmacoprevention for hereditary breast and ovarian cancer

被引：0
|
作者：
Cazzaniga, Massimiliano [1 ]
Bonanni, Bernardo [1 ]
机构：
[1] European Inst Oncol, Div Canc Prevent & Genet, Via Ripamonti 435, I-20141 Milan, Italy
来源：
MINERVA GINECOLOGICA | 2016年 / 68卷 / 05期
关键词：
Chemoprevention; Hereditary breast and ovarian cancer syndrome; Germ-line mutation;
D O I：
暂无
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Hereditary breast and ovarian cancer (HBOC) syndrome is an important women's health condition characterized by an increased susceptibility to the development of cancer, in particular breast and ovarian neoplasms, and is caused by an inherited germline genetic mutation in one or both tumor suppressor genes named BRCA1 and BRCA2. This monographic issue provides an update on our knowledge of this syndrome with particular emphasis on the risk reduction strategies through a pharmacopreventive approach.
引用
收藏
页码：517 / 535
页数：19
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