MULTIPLE ALIGNMENT OF SEQUENCES ON PARALLEL COMPUTERS

被引：0
|
作者：
DATE, S
KULKARNI, R
KULKARNI, B
KULKARNIKALE, U
KOLASKAR, AS
机构：
[1] UNIV POONA,CTR DEV ADV COMP,POONA 411007,MAHARASHTRA,INDIA
[2] UNIV POONA,DEPT ZOOL,DIC,CTR BIOINFORMAT,POONA 411007,MAHARASHTRA,INDIA
来源：
COMPUTER APPLICATIONS IN THE BIOSCIENCES | 1993年 / 9卷 / 04期
关键词：
D O I：
暂无
中图分类号：
TP39 [计算机的应用];
学科分类号：
081203 ; 0835 ;
摘要：
A software package that allows one to carry out multiple alignment of protein and nucleic acid sequences of almost unlimited length and number of sequences is developed on C-DAC parallel computer-a transputer-based machine. The farming approach is used for data parallelization. The speed gains are almost linear when the number of transputers is increased from 4 to 64. The software is used to carry out multiple alignment of 100 sequences each of alpha-chain and beta-chain of hemoglobin and 83 cytochrome c sequences. The signature sequence of cytochrome c was found to be PGTKMXF. The single parameter, multiple alignment score, S, has been used to categorize proteins in different subfamilies and groups.
引用
收藏
页码：397 / 402
页数：6
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