Potential benefits of vitamin D for patients with systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a Complex MUlti-system autoimmune disease. Vitamin D deficiency has been proposed as an environmental trigger of disease onset and as a contributor to increased SLE activity. SLE patients are prone to develop vitanlin D deficiency because of photosensitivity leading to sun avoidance and other sun protective measures. The impact of vitamin D on immune function previously seen in vitro and in cross-sectional studies has now been shown dies strengthening the evidence thatprospective human ate that there is a connection between SLE and vitamin D status. This review describes the role of vitamin D on immune function, prevalence of vitamin D deficiency in patients with SLE, identify risk factors for deficiency describe the consequences of deficiency in SLE patients, and review current vitamin D recommendations for patients with SLE.