Drug clinical trials on high-grade gliomas: challenges and hopes

被引：0
|
作者：
Mengqian Huang [1 ]
Shenglan Li [1 ]
Parker Li [2 ]
Zhuang Kang [1 ]
Botao Zhang [1 ]
Wenbin Li [1 ]
机构：
[1] Cancer Center, Beijing Tiantan Hospital, Capital Medical University
[2] Clinical Medicine, Shanghai Jiao Tong University School of Medicine
来源：
Cancer Biology & Medicine | 2023年 / 20卷 / 12期
关键词：
D O I：
暂无
中图分类号：
R739.4 [神经系肿瘤]; R969 [临床药理学];
学科分类号：
100214 ; 100602 ; 100706 ;
摘要：
Gliomas are the most common group of malignant central nervous system tumors across all ages and have high heterogeneity.According to histopathologic criteria and molecular pathology,gliomas are classified as grades 1-4.High-grade gliomas (HGG),including the most aggressive subtype,glioblastoma (GBM),belong to grade 3 or 4.Although a standard therapy comprising surgical resection,chemotherapy,and radiation is available,almost all patients with HGG experience recurrence within several months and a dismal prognosis1.
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收藏
页码：947 / 954
页数：8
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