基于生物信息学分析ATP6V0D2在肝细胞癌中的表达和预后价值

被引：0

作者：

黄小松 ^{[1
,2
]}

白洁 ^{[3
]}

黄怡倩 ^{[2
]}

机构：

[1] 浙江中医药大学研究生院

[2] 浙江大学医学院附属第四医院

[3] 不详

来源：

现代实用医学 | 2024年 / 36卷 / 01期

关键词：

ATP6V0D2; 肝细胞癌; 预后; 生物信息学;

D O I：

暂无

中图分类号：

R735.7 [肝肿瘤]; Q811.4 [生物信息论];

学科分类号：

0711 ; 0831 ;

摘要：

目的基于生物信息学分析ATP6V0D2在肝细胞癌(HCC)中的表达,以及与预后的关系。方法采用GEPIA及UALCAN数据库对ATP6V0D2进行分析,比较HCC组织与正常组织中ATP6V0D2的表达差异及与患者预后的关系。结果与正常组织相比,ATP6V0D2在HCC中高表达;高表达ATP6V0D2基因患者生存期低于低表达ATP6V0D2基因患者;不同临床分期患者ATP6V0D2基因表达差异无统计学意义(P>0.05);ATP6V0D2表达水平与甲胎蛋白(AFP)表达水平呈正相关(P <0.05)。结论 ATP6V0D2可能成为HCC新的治疗靶点及HCC诊断与预后的重要指标。

引用

页码：21 / 23

页数：3

共 13 条

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