Submesoscale processes in marginal seas usually have complex generating mechanisms, highly dependent on the local background flow and forcing. This numerical study investigates the spatial and seasonal differences of submesoscale activities in the upper ocean of the South China Sea (SCS) and the different dynamical regimes for sub-regions. The spatial and seasonal variations of vertical vorticity, horizontal convergence, lateral buoyancy gradient, and strain rate are analyzed to compare the submesoscale phenomenon within four sub-regions, the northern region near the Luzon Strait (R1), the middle ocean basin (R2), the western SCS (R3), and the southern SCS (R4). The results suggest that the SCS submesoscale processes are highly heterogeneous in space, with different seasonalities in each sub-region. The submesoscale activities in the northern sub-regions (R1, R2) are active in winter but weak in summer, while there appears an almost seasonal anti-phase in the western region (R3) compared to R1 and R2. Interestingly, no clear seasonality of submesoscale features is shown in the southern region (R4). Further analysis of Ertel potential vorticity reveals different generating mechanisms of submesoscale processes in different sub-regions. Correlation analyses also show the vertical extent of vertical velocity and the role of monsoon in generating submesoscale activities in the upper ocean of sub-regions. All these results suggest that the sub-regions have different regimes for submesoscale processes, e.g., Kuroshio intrusion (R1), monsoon modulation (R2), frontal effects (R3), topography wakes (R4).