IgE and mast cells in allergic disease

被引：0
|
作者：
Stephen J Galli
Mindy Tsai
机构：
[1] Stanford University School of Medicine,Department of Pathology
[2] Stanford University School of Medicine,Department of Microbiology and Immunology
来源：
Nature Medicine | 2012年 / 18卷
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摘要：
Both mast cells and IgE play crucial parts during the initiation and amplification of the allergic response during asthma, as well as during the tissue remodeling that occurs at the chronic stage. This review discusses how these two players can affect the development of asthma through independent and interdependent functions and the therapeutic implications for treating the clinical symptoms derived from allergic disease.
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页码：693 / 704
页数：11
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