Fibromyalgia as a sympathetically maintained pain syndrome

被引：89

作者：

Martinez-Lavin M. ^{[1
]}

机构：

[1] Rheumatology Department, Instituto Nacional de Cardiologia, 14080 Mexico DF

来源：

Current Pain and Headache Reports | 2004年 / 8卷 / 5期

关键词：

Heart Rate Variability; Neuropathic Pain; Fibromyalgia; Complex Regional Pain Syndrome; Reflex Sympathetic Dystrophy;

D O I：

10.1007/s11916-996-0012-4

中图分类号：

学科分类号：

摘要：

Abnormal activity of the sympathetic nervous system may be involved in the pathogenesis of chronic pain syndromes. This article reviews the animal studies of sympathetically induced pain behavior, the controversy of sympathetically maintained pain in clinical practice, and the dysautonomic nature of fibromyalgia (FM). FM has neuropathic pain features (stimuli-independent pain state accompanied by allodynia and paresthesias). The proposal of FM as a sympathetically maintained pain syndrome is based on the controlled studies showing that patients with FM display signs of relentless sympathetic hyperactivity and that the pain is submissive to sympathetic blockade and is rekindled by norepinephrine injections. Dysautonomia also may explain the multisystem features of FM. Copyright © 2004 by Current Science Inc.

引用

页码：385 / 389

页数：4

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