Susceptibility of SARS-CoV2 infection in children

被引:0
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作者
Nicola Cotugno
Donato Amodio
Danilo Buonsenso
Paolo Palma
机构
[1] Bambino Gesù Children’s Hospital,Clinical Immunology and Vaccinology Unit
[2] IRCCS,Chair of Pediatrics, Department of Systems Medicine
[3] University of Rome “Tor Vergata”,Department of Woman and Child Health and Public Health
[4] Fondazione Policlinico Universitario A Gemelli IRCCS,Centro di Salute Globale
[5] Università Cattolica del Sacro Cuore,undefined
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关键词
Pediatric COVID-19; Long-COVID; COVID-19 genetic susceptibility; COVID-19 vaccines; MIS-C;
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摘要
Coronavirus disease 2019 in children presents with distinct phenotype in comparison to adults. Overall, the pediatric infection with a generally milder clinical course of the acute infection compared to adults still faces several unknown aspects. Specifically, the presence of a wide range of inflammatory manifestations, including multisystem inflammatory syndrome in children (MIS-C), myocarditis, and long COVID in the period after infection suggests a particular susceptibility of some children upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Albeit peculiar complications such as long covid are less frequent in children compared to adults, research on the relationship between inflammatory syndromes and SARS-CoV-2 is rapidly evolving.
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页码:4851 / 4857
页数:6
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