Influence of various pharmaceutical factors on drug release from matrix tablets

被引：0
|
作者：
Bykov V.A. [1 ,2 ]
Demina N.B. [1 ]
Kemenova V.A. [2 ]
Velikaya E.V. [1 ]
Chulyukov O.G. [3 ]
机构：
[1] Sechenov Medical Academy, Moscow
[2] Scientific Center for Biomedical Technologies, State Research Institute of Medicinal and Aromatic Plants (VILAR), Moscow
[3] Lumex Company, Moscow
来源：
Pharmaceutical Chemistry Journal | 2005年 / 39卷 / 5期
关键词：
Polymer; Ethylene; Organic Chemistry; Ethylene Glycol; Drug Release;
D O I：
10.1007/s11094-005-0129-5
中图分类号：
学科分类号：
摘要：
The influence of various pharmaceutical factors on the release of active substances from matrix tablets based on interpolyelectrolyte complexes of poly(methacrylic acid) and poly(ethylene glycol) has been studied. By varying these factors, it is possible to control the drug release kinetics and create new medicinal forms with preset properties. The most important factors in this respect are the polymer fraction in the composition and the character of interaction between the active substance and matrix components. © 2005 Springer Science+Business Media, Inc.
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页码：265 / 270
页数：5
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