Fumaquinone, a New Prenylated Naphthoquinone from Streptomyces fumanus

被引：0
|
作者：
Romila D Charan
Gerhard Schlingmann
Valerie S Bernan
Xidong Feng
Guy T Carter
机构：
[1] Chemical and Screening Sciences,
[2] Wyeth Research,undefined
[3] Albany Molecular Research,undefined
来源：
The Journal of Antibiotics | 2005年 / 58卷
关键词：
prenylated naphthoquinone; actinomycete; fumaquinone; antibiotic; stable isotope labeling;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new prenylated naphthoquinone antibiotic, fumaquinone (5,7-dihydroxy-2-methoxy-3-methyl-6-(3-methyl-but-2-enyl)[1,4]naphthoquinone) was isolated from cultures of Streptomyces fumanus (LL-F42248). Its chemical structure was determined primarily by NMR spectroscopy. Preliminary feeding experiments indicated the naphthoquinone is of polyketide origin, while the O-methyl and aromatic C-methyl groups are derived from methionine.
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页码：271 / 274
页数：3
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