Chemokines and central nervous system disorders

被引:0
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作者
William J. Karpus
机构
[1] Northwestern University Medical School,Department of Pathology
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关键词
chemokines; chemokine receptors; demyelinating disease; central nervous system;
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摘要
Chemokines and their receptors are large families of inflammatory molecules responsible for a number of biologic functions including the accumulation of leukocytes at tissue sites. Over the past 8 years, a number of studies have indicated a role for chemokines in the pathogenesis of CNS inflammatory diseases. This minireview provides a brief summary of our current knowledge of chemokines and CNS inflammatory diseases including experimental autoimmune encephalomyelitis, multiple sclerosis, virus-induced demyelinating diseases, Alzheimer’s disease, and central nervous system bacterial-induced diseases.
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页码:493 / 500
页数:7
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