Data from the ARISTOTLE trial showed that apixaban, compared with warfarin, reduced the rates of stroke, death and major bleeding in patients with atrial fibrillation, regardless of renal function. Is the problem of balancing the risks of thromboembolism and bleeding in patients with atrial fibrillation and chronic kidney disease finally solved?
机构:
Univ Georgia, Dept Pharmaceut & Biomed Sci, Coll Pharm, Athens, GA 30602 USAUniv Georgia, Dept Pharmaceut & Biomed Sci, Coll Pharm, Athens, GA 30602 USA
Najahi-Missaoui, Wided
Arnold, Robert D.
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Auburn Univ, Harrison Sch Pharm, Dept Drug Discovery Dev, Auburn, AL 36849 USA
Univ Georgia, Interdisciplinary Toxicol Program, Athens, GA 30602 USAUniv Georgia, Dept Pharmaceut & Biomed Sci, Coll Pharm, Athens, GA 30602 USA
Arnold, Robert D.
Cummings, Brian S.
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Univ Georgia, Dept Pharmaceut & Biomed Sci, Coll Pharm, Athens, GA 30602 USA
Univ Georgia, Interdisciplinary Toxicol Program, Athens, GA 30602 USAUniv Georgia, Dept Pharmaceut & Biomed Sci, Coll Pharm, Athens, GA 30602 USA
机构:
Univ Texas Med Branch, Dept Internal Med, Div Rheumatol, Galveston, TX 77555 USAUniv Texas Med Branch, Dept Internal Med, Div Rheumatol, Galveston, TX 77555 USA
Pierangeli, S. S.
Erkan, D.
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Cornell Univ, Hosp Special Surg, Weill Med Coll, Barbara Volcker Ctr Women & Rheumat Dis, New York, NY 10021 USAUniv Texas Med Branch, Dept Internal Med, Div Rheumatol, Galveston, TX 77555 USA
机构:
Stanford Univ, Sch Med, Dept Gastroenterol, Stanford, CA 94305 USA
VA Palo Alto HCS, Stanford, CA USASoonchunhyang Univ, Coll Med, Dept Internal Med, Inst Digest Res, Seoul, South Korea