Development of NK cell-based cancer immunotherapies through receptor engineering

被引：0
|
作者：
Audrey Page
Nicolas Chuvin
Jenny Valladeau-Guilemond
Stéphane Depil
机构：
[1] Centre de Recherche en Cancérologie de Lyon,
[2] UMR INSERM U1052 CNRS 5286,undefined
[3] Centre Léon Bérard,undefined
[4] ErVimmune,undefined
[5] Centre Léon Bérard,undefined
[6] Université Claude Bernard Lyon 1,undefined
来源：
Cellular & Molecular Immunology | 2024年 / 21卷
关键词：
NK cells; Cell therapy; Receptor engineering; CAR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Natural killer (NK) cell-based immunotherapies are attracting increasing interest in the field of cancer treatment. Early clinical trials have shown promising outcomes, alongside satisfactory product efficacy and safety. Recent developments have greatly increased the therapeutic potential of NK cells by endowing them with enhanced recognition and cytotoxic capacities. This review focuses on surface receptor engineering in NK cell therapy and discusses its impact, challenges, and future directions.
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页码：315 / 331
页数：16
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