TGFβ-1 regulation of VEGF production by breast cancer cells

被引:0
|
作者
Declan Donovan
Judith H. Harmey
Deirdre Toomey
D. Henry Osborne
H. Paul Redmond
David J. Bouchier-Hayes
机构
[1] Beaumont Hospital,From the Royal College of Surgeons in Ireland, Department of Surgery
[2] Beaumont,undefined
来源
关键词
Vascular endothelial growth factor; Transforming growth factor β-1; Breast cancer; Angiogenesis; Metastasis;
D O I
暂无
中图分类号
学科分类号
摘要
Background: Angiogenesis is essential for tumor growth and metastasis. Vascular endothelial growth factor (VEGF) is the most potent angiogenic factor identified to date. TGFβ-1 acts as an indirect angiogenic agent.
引用
收藏
页码:621 / 627
页数:6
相关论文
共 50 条
  • [1] TGF beta-1 regulation of VEGF production by breast cancer cells
    Donovan, D
    Harmey, JH
    Toomey, D
    Osborne, DH
    Redmond, HP
    BouchierHayes, DJ
    [J]. ANNALS OF SURGICAL ONCOLOGY, 1997, 4 (08) : 621 - 627
  • [2] TGF-β1 mediated stimulation of VEGF secretion by breast cancer cells
    Costello, M.
    Dwyer, R. M.
    Ryan, J.
    Hartmann, M.
    Kerin, M. J.
    [J]. BRITISH JOURNAL OF SURGERY, 2011, 98 : 28 - 28
  • [3] Regulation and role of TGF beta production in breast cancer
    Knabbe, C
    Kopp, A
    Hilgers, W
    Lang, D
    Muller, V
    Zugmaier, G
    Jonat, W
    [J]. BASIS FOR CANCER MANAGEMENT, 1996, 784 : 263 - 276
  • [4] LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells
    Li, Nian-Shuang
    Zou, Jun-Rong
    Lin, Hui
    Ke, Rong
    He, Xiao-Ling
    Xiao, Lu
    Huang, Deqiang
    Luo, Lingyu
    Lv, Nonghua
    Luo, Zhijun
    [J]. TUMOR BIOLOGY, 2016, 37 (06) : 8249 - 8258
  • [5] Molecular mechanisms for leptin regulation of VEGF in breast cancer cells.
    Xu, Y.
    Watlers, A.
    Leibovich, S. J.
    Mann, D.
    Rueda, B. R.
    Gonzalez, R. R.
    [J]. CANCER RESEARCH, 2009, 69 (02) : 225S - 225S
  • [6] Production and oestrogen regulation of FGF1 in normal and cancer breast cells
    El Yazidi, I
    Renaud, F
    Laurent, M
    Courtois, Y
    Boilly-Marer, Y
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1998, 1403 (02): : 127 - 140
  • [7] Down-regulation of TGF-β1 production restores immunogenicity in prostate cancer cells
    Matthews, E.
    Yang, T.
    Janulis, L.
    Goodwin, S.
    Kundu, S. D.
    Karpus, W. J.
    Lee, C.
    [J]. BRITISH JOURNAL OF CANCER, 2000, 83 (04) : 519 - 525
  • [8] Down-regulation of TGF-β 1 production restores immunogenicity in prostate cancer cells
    E Matthews
    T Yang
    L Janulis
    S Goodwin
    S D Kundu
    W J Karpus
    C Lee
    [J]. British Journal of Cancer, 2000, 83 : 519 - 525
  • [9] Transcriptional regulation of osteopontin production by TGF-beta in breast cancer cells: Implications in metastasis and tumorigenicity.
    Hashimoto, N
    Yoneda, T
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2002, 17 : S171 - S171
  • [10] Production and regulation of interleukin-11 by breast cancer cells
    Lacroix, M
    Siwek, B
    Marie, PJ
    Body, JJ
    [J]. CANCER LETTERS, 1998, 127 (1-2) : 29 - 35