Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia

被引：0

作者：

Bin Zhang

Le Xuan Truong Nguyen

Ling Li

Dandan Zhao

Bijender Kumar

Herman Wu

Allen Lin

Francesca Pellicano

Lisa Hopcroft

Yu-Lin Su

Mhairi Copland

Tessa L Holyoake

Calvin J Kuo

Ravi Bhatia

David S Snyder

Haris Ali

Anthony S Stein

Casey Brewer

Huafeng Wang

Tinisha McDonald

Piotr Swiderski

Estelle Troadec

Ching-Cheng Chen

Adrienne Dorrance

Vinod Pullarkat

Yate-Ching Yuan

Danilo Perrotti

Nadia Carlesso

Stephen J Forman

Marcin Kortylewski

Ya-Huei Kuo

Guido Marcucci

机构：

[1] Gehr Family Center for Leukemia Research,Department of Medical Biotechnology

[2] Hematology Malignancies and Stem Cell Transplantation Institute,Department of Immuno

[3] City of Hope Medical Center,oncology

[4] Biotechnology Center of Ho Chi Minh City,Department of Hematology

[5] Paul O' Gorman Leukemia Research Centre,Division of Hematology, Department of Internal Medicine

[6] College of Medical,Department of Medicine

[7] Veterinary and Life Sciences,undefined

[8] Institute of Cancer Sciences,undefined

[9] University of Glasgow,undefined

[10] City of Hope Medical Center,undefined

[11] Stanford University School of Medicine,undefined

[12] University of Alabama at Birmingham,undefined

[13] First Affiliated Hospital,undefined

[14] Zhejiang University School of Medicine,undefined

[15] Ohio State University,undefined

[16] Biochemistry and Molecular Biology and the Marlene and Stewart Greenebaum Comprehensive Cancer Center,undefined

[17] University of Maryland School of Medicine Baltimore,undefined

[18] Deparment of Hematology,undefined

[19] Hammersmith Hospital,undefined

[20] Imperial College London,undefined

来源：

Nature Medicine | 2018年 / 24卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

In chronic myelogenous leukemia, leukemia stem cell function requires a microRNA that is provided by bone marrow endothelial cells.

引用

页码：450 / 462

页数：12

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[1] Bone marrow niche trafficking of miR-126 controls the self-renewal of leukemia stem cells in chronic myelogenous leukemia
Zhang, Bin
Le Xuan Truong Nguyen
Li, Ling
Zhao, Dandan
Kumar, Bijender
Wu, Herman
Lin, Allen
Pellicano, Francesca
Hopcroft, Lisa
Su, Yu-Lin
Copland, Mhairi
Holyoake, Tessa L.
Kuo, Calvin J.
Bhatia, Ravi
Snyder, David S.
Ali, Haris
Stein, Anthony S.
Brewer, Casey
Wang, Huafeng
McDonald, Tinisha
Swiderski, Piotr
Troadec, Estelle
Chen, Ching-Cheng
Dorrance, Adrienne
Pullarkat, Vinod
Yuan, Yate-Ching
Perrotti, Danilo
Carlesso, Nadia
Forman, Stephen J.
Kortylewski, Marcin
Kuo, Ya-Huei
Marcucci, Guido
[J]. NATURE MEDICINE, 2018, 24 (04) : 450 - +
[2] miR-126 Drives Quiescence and Self-Renewal in Leukemic Stem Cells
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Trumpp, Andreas
[J]. CANCER CELL, 2016, 29 (02) : 133 - 135
[3] miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells
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[J]. CANCER CELL, 2016, 29 (02) : 214 - 228
[4] Chronic versus acute myelogenous leukemia:: A question of self-renewal
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[J]. CANCER CELL, 2004, 6 (06) : 531 - 533
[5] Exosomal shuttling of miR-126 in endothelial cells modulates adhesive and migratory abilities of chronic myelogenous leukemia cells
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[J]. MOLECULAR CANCER, 2014, 13
[6] Exosomal shuttling of miR-126 in endothelial cells modulates adhesive and migratory abilities of chronic myelogenous leukemia cells
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[J]. Molecular Cancer, 13
[7] GADD45a Controls Self-Renewal in Acute Myeloid Leukemia Stem Cells
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[J]. BLOOD, 2020, 136
[8] Preservation of Quiescent Chronic Myelogenous Leukemia Stem Cells by the Bone Marrow Microenvironment
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[J]. BIOLOGICAL MECHANISMS OF MINIMAL RESIDUAL DISEASE AND SYSTEMIC CANCER, 2018, 1100 : 97 - 110
[9] Targeting Leukemia Stem Cells in the Bone Marrow Niche
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[J]. BIOMEDICINES, 2018, 6 (01)
[10] Gas6/AXL Signaling Regulates Self-Renewal of Chronic Myelogenous Leukemia Stem Cells by Stabilizing β-Catenin
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Pan, Jingxuan
[J]. CLINICAL CANCER RESEARCH, 2017, 23 (11) : 2842 - 2855

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