Genetics of diabetic retinopathy

被引:17
|
作者
Hanis C.L. [1 ]
Hallman D.M. [1 ]
机构
[1] Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX 77225
关键词
Diabetic Retinopathy; Genetic Susceptibility; Aldose Reductase; Diabetic Macular Edema; Familial Aggregation;
D O I
10.1007/s11892-006-0027-6
中图分类号
学科分类号
摘要
Diabetes is rapidly increasing in frequency with an attendant toll of complications, including diabetic retinopathy. Although the underlying mechanisms remain elusive, genetic susceptibility is key to both types 1 and 2 diabetes and is increasingly recognized for its contribution to diabetic complications. In this article we review the evidence connecting genetic susceptibility to diabetic retinopathy. Elucidating the susceptibility genes and pathways should permit strategies to slow and reverse the troubling trends for the population, families, and individuals. Copyright © 2006 by Current Science Inc.
引用
收藏
页码:155 / 161
页数:6
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