Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease

被引：0
|
作者：
Cem Kuscu
Sevki Arslan
Ritambhara Singh
Jeremy Thorpe
Mazhar Adli
机构：
[1] School of Medicine,Department of Biochemistry and Molecular Genetics
[2] University of Virginia,Department of Biology
[3] Pamukkale University,Department of Computer Science
[4] University of Virginia,undefined
来源：
Nature Biotechnology | 2014年 / 32卷
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摘要：
ChIP-seq for Cas9 shows varying amounts of off-target binding with different guide RNAs and low levels of indels at some off-target sites.
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页码：677 / 683
页数：6
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