People often test hypotheses about two variables (X andY), each with two levels (e.g.,X1 andX2). When testing “IfX1, thenY1,” observing the conjunction ofX1 andY1 is overwhelmingly perceived as more supportive than observing the conjunction ofX2 andY2, although both observations support the hypothesis. Normatively, theX2&Y2 observation provides stronger support than theX1&Y1 observation if the former is rarer. Because participants in laboratory settings typically test hypotheses they are unfamiliar with, previous research has not examined whether participants are sensitive to the rarity of observations. The experiment reported here showed that participants were sensitive to rarity, even judging a rareX2&Y2 observation more supportive than a commonX1&Y1 observation under certain conditions. Furthermore, participants’ default strategy of judgingX1&Y1 observations more informative might be generally adaptive because hypotheses usually regard rare events.