Population Pharmacokinetics, Efficacy Exposure-response Analysis, and Model-based Meta-analysis of Fenebrutinib in Subjects with Rheumatoid Arthritis

被引:0
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作者
Phyllis Chan
Jiajie Yu
Leslie Chinn
Marita Prohn
Jan Huisman
Brett Matzuka
William Hanley
Katie Tuckwell
Angelica Quartino
机构
[1] Clinical Pharmacology,Clinical Sciences
[2] qPharmetra,undefined
[3] qPharmetra,undefined
[4] Former Genentech employee,undefined
[5] currently of Seattle Genetics,undefined
[6] Early Clinical Development,undefined
关键词
Bruton’s tyrosine kinase (BTK) inhibitor; exposure-response; model-based meta-analysis; population pharmacokinetics; rheumatoid arthritis;
D O I
10.1007/s11095-019-2752-y
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