LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases--a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial

被引:0
|
作者
Carl Christoph Schimanski
Markus Möhler
Michael Schön
Eric van Cutsem
Richard Greil
Wolf Otto Bechstein
Susanna Hegewisch-Becker
Götz von Wichert
Matthias Vöhringer
Michael Heike
Volker Heinemann
Marc Peeters
Stephan Kanzler
Stefan Kasper
Friedrich Overkamp
Jan Schröder
Daniel Seehofer
Frank Kullmann
Bernhard Linz
Irene Schmidtmann
Victoria Smith-Machnow
Ines Gockel
Hauke Lang
Peter R Galle
机构
[1] University Medical Center (UMC),First Deptartment of Internal Medicine
[2] University Hospital of Mainz,Department of General and Abdominal Surgery
[3] Municipal Hospital of Karlsruhe,Digestive Oncology Unit
[4] University Hospital Gasthuisberg,Third Department of Internal Medicine
[5] University Medical Center (UMC),Department of General and Abdominal Surgery
[6] University Hospital of Salzburg,First Department of Internal Medicine
[7] University Medical Center (UMC),Center of Internal Medicine
[8] University Hospital of Frankfurt,Med. Klinik Mitte
[9] Onkologische Schwerpunktpraxis Eppendorf,Third Department of Internal Medicine
[10] University Medical Center (UMC),Department of Oncology
[11] University Hospital of Ulm,Department of Internal Medicine
[12] Robert-Bosch Hospital,Department of Internal Medicine
[13] Hospital of Dortmund,Outpatient center for hematology and oncology
[14] University Hospital of Großhadern,Department of General, Visceral and Transplantation Surgery
[15] Antwerp University Hospital,First Department of Internal Medicine
[16] Leopoldina Hospital,Institute of Medical Biometrics, Epidemiology and Informatics (IMBEI)
[17] University Medical Center (UMC),Department of General and Abdominal Surgery
[18] University Hospital of Essen,First Dept. of Internal Medicine
[19] Oncologianova GmbH,undefined
[20] Mühlheim an der Ruhr,undefined
[21] Campus Virchow Klinikum,undefined
[22] Humboldt University,undefined
[23] Kliniken Nordoberpfalz AG,undefined
[24] Outpatient center for hematology and oncology,undefined
[25] University Medical Center (UMC),undefined
[26] University Hospital of Mainz,undefined
[27] iOMEDICO,undefined
[28] University Medical Center (UMC),undefined
[29] University Hospital of Mainz,undefined
[30] University Medical Center (UMC),undefined
[31] University Hospital of Mainz,undefined
来源
BMC Cancer | / 12卷
关键词
Liver Metastasis; Hepatic Metastasis; DPPC; ECOG Performance Status; MUC1 Expression;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases-a randomized, placebo-controlled, multicenter, multinational, double-blinded phase II trial
    Schimanski, Carl Christoph
    Moehler, Markus
    Schoen, Michael
    van Cutsem, Eric
    Greil, Richard
    Bechstein, Wolf Otto
    Hegewisch-Becker, Susanna
    von Wichert, Goetz
    Voehringer, Matthias
    Heike, Michael
    Heinemann, Volker
    Peeters, Marc
    Kanzler, Stephan
    Kasper, Stefan
    Overkamp, Friedrich
    Schroeder, Jan
    Seehofer, Daniel
    Kullmann, Frank
    Linz, Bernhard
    Schmidtmann, Irene
    Smith-Machnow, Victoria
    Gockel, Ines
    Lang, Hauke
    Galle, Peter R.
    BMC CANCER, 2012, 12
  • [2] LICC: L-BLP25 in patients with colorectal carcinoma after curative resection of hepatic metastases-A randomized, double-blind, placebo-controlled, multicenter, multinational, phase II trial.
    Schimanski, C. C.
    Galle, P. R.
    Lang, H.
    Schoen, M.
    Moehler, M. H.
    JOURNAL OF CLINICAL ONCOLOGY, 2011, 29 (15)
  • [3] A randomized, double-blinded, placebo-controlled multicenter phase II trial of adjuvant immunotherapy with tecemotide (L-BLP25) after R0/R1 hepatic colorectal cancer metastasectomy (LICC): Final results.
    Schimanski, Carl Christoph
    Kasper, Stefan
    Hegewisch-Becker, Susanna
    Schroeder, Jan
    Overkamp, Friedrich
    Kullmann, Frank
    Bechstein, Wolf Otto
    Vohringer, Matthias
    Oellinger, Robert
    Lordick, Florian
    Heinemann, Volker
    Geissler, Michael
    Schulz-Abelius, Armin
    Linz, Bernhard
    Bernhard, Helga
    Schoen, Michael R.
    Greil, Richard
    Smith-Machnow, Victoria
    Schmidtmann, Irene
    Moehler, Markus Hermann
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (04)
  • [4] A randomized, double-blinded, placebo-controlled multicenter phase II trial of adjuvant immunotherapy with tecemotide (L-BLP25) after R0/R1 hepatic colorectal cancer metastasectomy (LICC): Final results.
    Schimanski, Carl Christoph
    Kasper, Stefan
    Hegewisch-Becker, Susanna
    Schroeder, Jan
    Overkamp, Friedrich
    Kullmann, Frank
    Bechstein, Wolf Otto
    Voehringer, Matthias
    Oellinger, Robert
    Lordick, Florian
    Heinemann, Volker
    Geissler, Michael
    Schulz-Abelius, Armin
    Linz, Bernhard
    Bernhard, Helga
    Schoen, Michael R.
    Greil, Richard
    Smith-Machnow, Victoria
    Schmidtmann, Irene
    Moehler, Markus Hermann
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [5] A randomized, double-blind, placebo-controlled, multicenter, multinational, phase II trial of immunotherapy with L-BLP25 in patients with colorectal carcinoma following R0/R1 hepatic metastasectomy
    Schimanski, C. C.
    Moehler, M.
    Lang, H.
    Smith-Machnow, V
    Kanzler, S.
    Hegewisch-Becker, S.
    Doerfel, S.
    Seehofer, D.
    Bechstein, W. O.
    Heike, M.
    Overkamp, F.
    Kullmann, F.
    Voehringer, M.
    Heinemann, V
    von Wichert, G.
    Kasper, S.
    Greil, R.
    Schroeder, J.
    Galle, P. R.
    Schoen, M.
    ONKOLOGIE, 2012, 35 : 57 - 57
  • [6] A randomized, double-blind, placebo-controlled, multicenter, multinational, phase II trial immunotherapy with L-BLP25 (tecemotide) in patients with colorectal carcinoma following R0/R1 hepatic metastasectomy
    Kasper, Stefan
    Overkamp, Friedrich
    Moehler, Markus Hermann
    Kullmann, Frank
    Lang, Hauke
    Schoen, Michael
    Smith-Machnow, Victoria
    Hegewisch-Becker, Susanna
    Seehofer, Daniel
    Bechstein, Wolf
    Heike, Michael
    Voehringer, Matthias
    Heinemann, Volker
    Greil, Richard
    Geissler, Michael
    Lordick, Florian
    Peeters, Marc
    Van Cutsem, Eric
    Galle, Peter Robert
    Schimanski, Carl Christoph
    JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
  • [7] Adjuvant MUC vaccination with tecemotide after resection of colorectal liver metastases: a randomized, double-blind, placebo-controlled, multicenter AIO phase II trial (LICC)
    Schimanski, Carl Christoph
    Kasper, Stefan
    Hegewisch-Becker, Susanna
    Schroeder, Jan
    Overkamp, Friedrich
    Kullmann, Frank
    Bechstein, Wolf Otto
    Voehringer, Matthias
    Oellinger, Robert
    Lordick, Florian
    Heinemann, Volker
    Geissler, Michael
    Schulz-Abelius, Armin
    Bernhard, Helga
    Schoen, Michael R.
    Greil, Richard
    Galle, Peter
    Lang, Hauke
    Schmidtmann, Irene
    Moehler, Markus
    ONCOIMMUNOLOGY, 2020, 9 (01):
  • [8] A randomized, double-blind, placebo-controlled, multicenter, binational, phase II trial of immunotherapy with L-BLP25 (tecemotide) in patients with colorectal carcinoma following R0/R1 hepatic metastasectomy.
    Kasper, Stefan
    Moehler, Markus
    Hegewisch-Becker, Susanna
    Overkamp, Friedrich
    Bechstein, Wolf O.
    Kullmann, Frank
    Lang, Hauke
    Schoen, Michael
    Smith-Machnow, Victoria
    Seehofer, Daniel
    Voehringer, Matthias
    Geissler, Michael
    Greil, Richard
    Heike, Michael
    Heinemann, Volker
    Lordick, Florian
    Galle, Peter R.
    Schimanski, Carl Christoph
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [9] Famitinib versus placebo in the treatment of refractory metastatic colorectal cancer: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical trial
    Xu, Rui-Hua
    Shen, Lin
    Wang, Ke-Ming
    Wu, Gang
    Shi, Chun-Mei
    Ding, Ke-Feng
    Lin, Li-Zhu
    Wang, Jin-Wan
    Xiong, Jian-Ping
    Wu, Chang-Ping
    Li, Jin
    Liu, Yun-Peng
    Wang, Dong
    Ba, Yi
    Feng, Jue-Ping
    Bai, Yu-Xian
    Bi, Jing-Wang
    Ma, Li-Wen
    Lei, Jian
    Yang, Qing
    Yu, Hao
    CHINESE JOURNAL OF CANCER, 2017, 36
  • [10] Famitinib versus placebo in the treatment of refractory metastatic colorectal cancer:a multicenter, randomized,double-blinded,placebo-controlled,phase Ⅱclinical trial
    RuiHua Xu
    Lin Shen
    KeMing Wang
    Gang Wu
    ChunMei Shi
    KeFeng Ding
    LiZhu Lin
    JinWan Wang
    JianPing Xiong
    ChangPing Wu
    Jin Li
    YunPeng Liu
    Dong Wang
    Yi Ba
    JuePing Feng
    YuXian Bai
    JingWang Bi
    LiWen Ma
    Jian Lei
    Qing Yang
    Hao Yu
    Chinese Journal of Cancer, 2017, 36 (12) : 677 - 685