Population Pharmacokinetics and Bayesian Estimation of Mycophenolic Acid Concentrations in Stable Renal Transplant Patients

被引：0
|
作者：
Chantal Le Guellec
Hélène Bourgoin
Matthias Büchler
Yann Le Meur
Yvon Lebranchu
Pierre Marquet
Gilles Paintaud
机构：
[1] Tours University Hospital,Department of Pharmacology
[2] Tours University,Haematopoïetic Stem Cells and Haemostasis in Transplantation Research Group (EA 3249 and IFR 120)
[3] Tours University Hospital,Department of Nephrology and Clinical Immunology
[4] Limoges University Hospital,Department of Nephrology
[5] Limoges University Hospital,Department of Pharmacology and Toxicology
[6] Bretonneau University Hospital,Department of Pharmacology
来源：
Clinical Pharmacokinetics | 2004年 / 43卷
关键词：
Therapeutic Drug Monitoring; Mycophenolate Mofetil; Bayesian Estimation; Renal Transplant Patient; Population Pharmacokinetic Model;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Therapeutic drug monitoring of mycophenolic acid (MPA) may minimise the risk of acute rejection after transplantation. Area under the curve (AUC) rather than trough concentration-based monitoring is recommended and models for AUC estimation are needed.
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页码：253 / 266
页数：13
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