The association between p53 protein phosphorylation at serine 15, serine 20 and sensitivity of cells isolated from patients with ovarian cancer and cell lines to chemotherapy in in vitro study

被引:1
|
作者
Iwona Kamińska
Julia K. Bar
机构
[1] Medical University,Department of Immunopathology and Molecular Biology
来源
Pharmacological Reports | 2018年 / 70卷
关键词
Ovarian cancer cells; Ovarian cell lines; p53 phosphorylation; Serine 15; Serine 20;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:570 / 576
页数:6
相关论文
共 16 条
  • [1] The association between p53 protein phosphorylation at serine 15, serine 20 and sensitivity of cells isolated from patients with ovarian cancer and cell lines to chemotherapy in in vitro study
    Kaminska, Iwona
    Bar, Julia K.
    PHARMACOLOGICAL REPORTS, 2018, 70 (03) : 570 - 576
  • [2] The DNA binding and accumulation of p53 from breast cancer cell lines and the link with serine 15 phosphorylation
    Ray, Debolina
    Murphy, Keith R.
    Gal, Susannah
    CANCER BIOLOGY & THERAPY, 2012, 13 (10) : 848 - 857
  • [3] Association between p53 protein phosphorylated at serine 20 expression and ovarian carcinoma stem cells phenotype: correlation with clinicopathological parameters of ovarian cancer
    Bar, J.
    Grelewski, P.
    Deszcz, I.
    Noga, L.
    Hirnle, L.
    Lis-Nawara, A.
    NEOPLASMA, 2019, 66 (05) : 801 - 809
  • [4] Time and dose-dependent activation of p53 serine 15 phosphorylation among cell lines with different radiation sensitivity
    Wittlinger, Michael
    Grabenbauer, Gerhard G.
    Sprung, Carl N.
    Sauer, Rolf
    Distel, Luitpold V. R.
    INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2007, 83 (04) : 245 - 257
  • [5] Blockage of NF-κB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells
    Zerbini, LF
    Wang, YH
    Correa, RG
    Cho, JY
    Libermann, TA
    CELL CYCLE, 2005, 4 (09) : 1247 - 1253
  • [6] Actinomycin D and nutlin-3a synergistically promote phosphorylation of p53 on serine 46 in cancer cell lines of different origin
    Zajkowicz, Artur
    Gdowicz-Klosok, Agnieszka
    Krzesniak, Malgorzata
    Scieglinska, Dorota
    Rusin, Marek
    CELLULAR SIGNALLING, 2015, 27 (09) : 1677 - 1687
  • [7] Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes
    Amano, Toshiyuki
    Nakamizo, Akira
    Mishra, Sandip K.
    Gumin, Joy
    Shinojima, Naoki
    Sawaya, Raymond
    Lang, Frederick F.
    JOURNAL OF NEURO-ONCOLOGY, 2009, 92 (03) : 357 - 371
  • [8] Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes
    Toshiyuki Amano
    Akira Nakamizo
    Sandip K. Mishra
    Joy Gumin
    Naoki Shinojima
    Raymond Sawaya
    Frederick F. Lang
    Journal of Neuro-Oncology, 2009, 92
  • [9] Effect of distinct anticancer drugs on the phosphorylation of p53 protein at serine 46 in human MCF-7 breast cancer cells
    Wesierska-Gadek, Jozefa
    Gueorguieva, Marieta
    Herbacek, Irene
    Ranftler, Carmen
    SIGNAL TRANSDUCTION PATHWAYS, PT C: CELL SIGNALING IN HEALTH AND DISEASE, 2007, 1095 : 45 - 52
  • [10] Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells
    Balmer, Matthew T.
    Katz, Ryan D.
    Liao, Si
    Goodwine, James S.
    Gal, Susannah
    CANCER BIOLOGY & THERAPY, 2014, 15 (08) : 1000 - 1012