Microsatellite instability in colorectal cancer—the stable evidence

被引：0
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作者：
Eduardo Vilar
Stephen B. Gruber
机构：
[1] University of Michigan Comprehensive Cancer Center,Department of Internal Medicine
[2] University of Michigan Medical School,undefined
来源：
Nature Reviews Clinical Oncology | 2010年 / 7卷
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摘要：
Microsatellite instability (MSI) is a frequent molecular phenomenon of colorectal cancer and is associated with deficient DNA mismatch repair. This Review presents an overview of MSI, including its clinical features and applications. The authors discuss the prognostic and predictive value of MSI and how it can be used to improve our knowledge of other cancer subtypes.
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页码：153 / 162
页数：9
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