Redirecting abiraterone metabolism to fine-tune prostate cancer anti-androgen therapy

被引:0
|
作者
Zhenfei Li
Mohammad Alyamani
Jianneng Li
Kevin Rogacki
Mohamed Abazeed
Sunil K. Upadhyay
Steven P. Balk
Mary-Ellen Taplin
Richard J. Auchus
Nima Sharifi
机构
[1] Lerner Research Institute,Department of Cancer Biology
[2] Cleveland Clinic,Department of Radiation Oncology
[3] Taussig Cancer Institute,Departments of Pharmacology and Internal Medicine, Division of Endocrinology and Metabolism
[4] Cleveland Clinic,Department of Urology
[5] University of Michigan Medical School,Department of Hematology and Oncology
[6] Beth Israel Deaconess Medical Center,undefined
[7] Harvard Medical School,undefined
[8] Dana-Farber Cancer Institute,undefined
[9] Harvard Medical School,undefined
[10] Glickman Urological and Kidney Institute,undefined
[11] Cleveland Clinic,undefined
[12] Taussig Cancer Institute,undefined
[13] Cleveland Clinic,undefined
来源
Nature | 2016年 / 533卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The prostate cancer drug abiraterone can be metabolized into several substances with different effects, and optimization of this process could be helpful for fine-tuning the treatment of prostate cancer.
引用
收藏
页码:547 / 551
页数:4
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