Non-Competitive Inhibitory Activities of Morphinan and Morphine Derivatives at the α3β4 Neuronal Nicotinic Acetylcholine Receptor Determined Using Nonlinear Chromatography and Chemometric Techniques

被引:0
|
作者
Krzysztof Jozwiak
Ruin Moaddel
Rika Yamaguchi
Alexandre Maciuk
Irving W. Wainer
机构
[1] National Institute on Aging/NIH,Gerontology Research Center
[2] Medical University of Lublin,Department of Chemistry
[3] Shionogi & Co.,Bioanalytical and Drug Discovery Unit
[4] National Institute on Aging,undefined
[5] National Institutes of Health,undefined
[6] Gerontology Research Center,undefined
来源
Pharmaceutical Research | 2006年 / 23卷
关键词
affinity chromatography; functional assays; luminal binding site; molecular modeling; quinacrine binding site;
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学科分类号
摘要
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页码:2175 / 2182
页数:7
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