Neuroimaging in frontotemporal lobar degeneration—predicting molecular pathology

被引：0
|
作者：
Jennifer L. Whitwell
Keith A. Josephs
机构：
[1] Mayo Clinic,Department of Radiology
[2] Mayo Clinic,Department of Neurology
来源：
Nature Reviews Neurology | 2012年 / 8卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Predicting the molecular pathology that underlies neurodegeneration in patients with frontotemporal lobar degeneration (FTLD) is crucial to determine how to treat each individual. Whitwell and Josephs show how patterns of atrophy assessed on MRI can be used to identify signatures of pathology for each specific diagnosis within this broad spectrum of diseases. The authors discuss how these patterns of atrophy could be used as biomarkers of FTLD.
引用
收藏
页码：131 / 142
页数：11
相关论文
共 50 条
  • [1] Neuroimaging in frontotemporal lobar degeneration-predicting molecular pathology
    Whitwell, Jennifer L.
    Josephs, Keith A.
    NATURE REVIEWS NEUROLOGY, 2012, 8 (03) : 131 - 142
  • [2] From frontotemporal lobar degeneration pathology to frontotemporal lobar degeneration biomarkers
    Hales, Chadwick M.
    Hu, William T.
    INTERNATIONAL REVIEW OF PSYCHIATRY, 2013, 25 (02) : 210 - 220
  • [3] Pathology and genetics of frontotemporal lobar degeneration: an update
    Tolnay, M.
    Frank, S.
    CLINICAL NEUROPATHOLOGY, 2007, 26 (04) : 143 - 156
  • [4] Neuroimaging in Frontotemporal Lobar Degeneration: Research and Clinical Utility
    Dev, Sheena I.
    Dickerson, Bradford C.
    Touroutoglou, Alexandra
    FRONTOTEMPORAL DEMENTIAS: EMERGING MILESTONES OF THE 21ST CENTURY, 2021, 1281 : 93 - 112
  • [5] A review of the recent advances in neuroimaging of frontotemporal lobar degeneration
    D'Agata, Federico
    Orsi, Laura
    Cicerale, Alessandro
    Rubino, Elisa
    Rainero, Innocenzo
    Bergui, Mauro
    Pinessi, Lorenzo
    JOURNAL OF NEUROSURGICAL SCIENCES, 2017, 61 (02) : 180 - 192
  • [6] Argyrophilic grains pathology in frontotemporal lobar degeneration
    Gil Moreno, M.
    Manzano Palomo, M.
    Cuadrado Perez, M.
    Rabano Gutierrez, A.
    JOURNAL OF NEUROCHEMISTRY, 2016, 138 : 330 - 330
  • [7] FRONTOTEMPORAL LOBAR DEGENERATION: INSIGHTS FROM NEUROPSYCHOLOGY AND NEUROIMAGING
    Bozoki, Andrea C.
    Farooq, Muhammad U.
    NEUROBIOLOGY OF DEMENTIA, 2009, 84 : 185 - +
  • [8] Neuroimaging findings in frontotemporal lobar degeneration spectrum of disorders
    Agosta, Federica
    Canu, Elisa
    Sarro, Lidia
    Comi, Giancarlo
    Filippi, Massimo
    CORTEX, 2012, 48 (04) : 389 - 413
  • [9] Molecular Pathways of Frontotemporal Lobar Degeneration
    Sleegers, Kristel
    Cruts, Marc
    Van Broeckhoven, Christine
    ANNUAL REVIEW OF NEUROSCIENCE, VOL 33, 2010, 33 : 71 - 88
  • [10] The Molecular Genetics of Frontotemporal lobar Degeneration
    Pickering-Brown, Stuart
    JOURNAL OF MEDICAL GENETICS, 2012, 49 : S25 - S25
12345