A Novel Ras Antagonist Regulates Both Oncogenic Ras and the Tumor Suppressor p53 in Colon Cancer Cells

被引：0
|
作者：
Julius Halaschek-Wiener
Volker Wacheck
Hermine Schlagbauer-Wadl
Klaus Wolff
Yoel Kloog
Burkhard Jansen
机构：
[1] Section of Experimental Oncology/Molecular Pharmacology,Department of Clinical Pharmacology
[2] Division of General Dermatology,Department of Dermatology
[3] Tel Aviv University,Department of Neurobiochemistry, The George S. Wise Faculty of Life Sciences
来源：
Molecular Medicine | 2000年 / 6卷
关键词：
Colon Cancer Cells; FTS Treatment; Trans-farnesylthiosalicylic Acid; Treatment-resistant Malignancies; Cyclin Cyclin-dependent Kinases (CDK);
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：693 / 704
页数：11
相关论文
共 50 条
  • [1] A novel Ras antagonist regulates both oncogenic Ras and the tumor suppressor p53 in colon cancer cells
    Halaschek-Wiener, J
    Wacheck, V
    Schlagbauer-Wadl, H
    Wolff, K
    Kloog, Y
    Jansen, B
    MOLECULAR MEDICINE, 2000, 6 (08) : 693 - 704
  • [2] Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility
    Mingxuan Xia
    Hartmut Land
    Nature Structural & Molecular Biology, 2007, 14 : 215 - 223
  • [3] Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility
    Xia, Mingxuan
    Land, Hartmut
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2007, 14 (03) : 215 - 223
  • [4] PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
    Mark Pearson
    Roberta Carbone
    Carla Sebastiani
    Mario Cioce
    Marta Fagioli
    Shin’ichi Saito
    Yuichiro Higashimoto
    Ettore Appella
    Saverio Minucci
    Pier Paolo Pandolfi
    Pier Giuseppe Pelicci
    Nature, 2000, 406 : 207 - 210
  • [5] PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
    Pearson, M
    Carbone, R
    Sebastiani, C
    Cioce, M
    Fagioli, M
    Saito, S
    Higashimoto, Y
    Appella, E
    Minucci, S
    Pandolfi, PP
    Pelicci, PG
    NATURE, 2000, 406 (6792) : 207 - 210
  • [6] Ras oncogenes and p53 tumor suppressor gene analysis in cardiac myxomas
    Karga, H
    Papaioannou, P
    Karayianni, M
    Papadimitriou, K
    Priftis, D
    Voujuklakis, T
    Migdou, B
    Nanas, J
    Papapetrou, P
    PATHOLOGY RESEARCH AND PRACTICE, 2000, 196 (09) : 601 - 605
  • [7] Mutations of the p53 tumor suppressor gene and ras oncogenes in aflatoxin hepatocarcinogenesis
    Shen, HM
    Ong, CN
    MUTATION RESEARCH-REVIEWS IN GENETIC TOXICOLOGY, 1996, 366 (01): : 23 - 44
  • [8] Curcumin impairs tumor suppressor p53 function in colon cancer cells
    Moos, PJ
    Edes, K
    Mullally, JE
    Fitzpatrick, FA
    CARCINOGENESIS, 2004, 25 (09) : 1611 - 1617
  • [9] Oncogenic ras and p53 cooperate to induce cellular senescence
    Ferbeyre, G
    de Stanchina, E
    Lin, AW
    Querido, E
    McCurrach, ME
    Hannon, GJ
    Lowe, SW
    MOLECULAR AND CELLULAR BIOLOGY, 2002, 22 (10) : 3497 - 3508
  • [10] MUTAGENESIS OF THE H-RAS PROTOONCOGENE AND THE P53 TUMOR-SUPPRESSOR GENE
    CERUTTI, P
    HUSSAIN, P
    POURZAND, C
    AGUILAR, F
    CANCER RESEARCH, 1994, 54 (07) : S1934 - S1938
12345