Ythdf2-mediated m6A mRNA clearance modulates neural development in mice

被引:0
|
作者
Miaomiao Li
Xu Zhao
Wei Wang
Hailing Shi
Qingfei Pan
Zhike Lu
Sonia Peña Perez
Rajikala Suganthan
Chuan He
Magnar Bjørås
Arne Klungland
机构
[1] Oslo University Hospital,Department of Microbiology
[2] University of Oslo,Department of Molecular Medicine, Institute of Basic Medical Sciences
[3] Norwegian University of Science and Technology (NTNU),Department of Clinical and Molecular Medicine
[4] The University of Chicago,Department of Chemistry, Institute for Biophysical Dynamics
[5] The University of Chicago,Howard Hughes Medical Institute
[6] St. Jude Children’s Hospital,Department of Computational Biology
来源
关键词
Ythdf2; -methyladenosine (m; A); Neural development; Neurogenesis; mRNA clearance;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Ythdf2-mediated m6A mRNA clearance modulates neural development in mice
    Li, Miaomiao
    Zhao, Xu
    Wang, Wei
    Shi, Hailing
    Pan, Qingfei
    Lu, Zhike
    Perez, Sonia Pena
    Suganthan, Rajikala
    He, Chuan
    Bjoras, Magnar
    Klungland, Arne
    GENOME BIOLOGY, 2018, 19
  • [2] Binding to m6A RNA promotes YTHDF2-mediated phase separation
    Wang, Jiahua
    Wang, Liyong
    Diao, Jianbo
    Shi, Yujiang Geno
    Shi, Yang
    Ma, Honghui
    Shen, Hongjie
    PROTEIN & CELL, 2020, 11 (04) : 304 - 307
  • [3] Understanding YTHDF2-mediated mRNA degradation by m6A-BERT-Deg
    Zhang, Ting-He
    Jo, Sumin
    Zhang, Michelle
    Wang, Kai
    Gao, Shou-Jiang
    Huang, Yufei
    BRIEFINGS IN BIOINFORMATICS, 2024, 25 (03)
  • [4] Loss of YTHDF2-mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration
    Hu Wang
    Hongna Zuo
    Jin Liu
    Fei Wen
    Yawei Gao
    Xudong Zhu
    Bo Liu
    Feng Xiao
    Wengong Wang
    Gang Huang
    Bin Shen
    Zhenyu Ju
    Cell Research, 2018, 28 : 1035 - 1038
  • [5] Loss of YTHDF2-mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration
    Wang, Hu
    Zuo, Hongna
    Liu, Jin
    Wen, Fei
    Gao, Yawei
    Zhu, Xudong
    Liu, Bo
    Xiao, Feng
    Wang, Wengong
    Huang, Gang
    Shen, Bin
    Ju, Zhenyu
    CELL RESEARCH, 2018, 28 (10) : 1035 - 1038
  • [7] m6A/YTHDF2-mediated mRNA decay targets TGF-b signaling to suppress the quiescence acquisition of early postnatal mouse hippocampal NSCs
    Zhang, Feng
    Fu, Yao
    Jimenez-Cyrus, Dennisse
    Zhao, Ting
    Shen, Yachen
    Sun, Yusha
    Zhang, Zhijian
    Wang, Qing
    Kawaguchi, Riki
    Geschwind, Daniel H.
    He, Chuan
    Ming, Guo-li
    Song, Hongjun
    CELL STEM CELL, 2025, 32 (01)
  • [8] YTHDF2-Mediated m6A methylation inhibition by miR27a as a protective mechanism against hormonal osteonecrosis in BMSCs
    Yuan, Tianyi
    Liu, Hongjiang
    Abudoukadier, Maimaitiyibubaji
    Yang, Zengqiang
    Zhou, Zhiheng
    Cui, Yong
    BMC MUSCULOSKELETAL DISORDERS, 2024, 25 (01)
  • [9] YTHDF2-mediated m6A modification of ONECUT2 promotes stemness and oxaliplatin resistance in gastric cancer through transcriptionally activating TFPI
    Fan, Xingdi
    Han, Fangyi
    Wang, Haocheng
    Shu, Zhilin
    Qiu, Bowen
    Zeng, Fanan
    Chen, Hongzhen
    Wu, Ziying
    Lin, Yongwei
    Lan, Zhien
    Ye, Zhiwei
    Ying, Yao
    Geng, Tiansu
    Xian, Ziqian
    Niu, Xing
    Wu, Junming
    Mo, Ke
    Zheng, Kehong
    Ye, Yaping
    Cui, Chunhui
    DRUG RESISTANCE UPDATES, 2025, 79
  • [10] Fufang Zhenzhu Tiaozhi (FTZ) capsule ameliorates diabetes-accelerated atherosclerosis via suppressing YTHDF2-mediated m6A modification of SIRT3 mRNA
    Zhang, Yue
    Wang, Ruonan
    Tan, Huiling
    Wu, Kaili
    Hu, Yaju
    Diao, Hongtao
    Wang, Dongwei
    Tang, Xinyuan
    Leng, Mingyang
    Li, Xu
    Cai, Zhenlu
    Luo, Duosheng
    Shao, Xiaoqi
    Yan, Meiling
    Chen, Yingyu
    Rong, Xianglu
    Guo, Jiao
    JOURNAL OF ETHNOPHARMACOLOGY, 2023, 317