Modeling of mitochondrial bioenergetics and autophagy impairment in MELAS-mutant iPSC-derived retinal pigment epithelial cells

被引：0
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作者：
Sujoy Bhattacharya
Jinggang Yin
Weihong Huo
Edward Chaum
机构：
[1] Vanderbilt University Medical Center,Department of Ophthalmology and Visual Sciences
来源：
Stem Cell Research & Therapy | / 13卷
关键词：
Age-related macular degeneration; MELAS; iPSC-derived retinal pigment epithelium; Autophagy flux; Mitophagy; Mitochondrial heteroplasmy; Prom1/CD133; AMPKα; PGC-1α; Regenerative medicine;
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