Central nervous system involvement in Hodgkin´s lymphoma is extremely rare. We report three cases who had a relapse from the disease involving CNS. The most frequent causes are skull contiguity, meningeal invasion and via the hematogenous route. It is frequent that the association between Epstein–Barr Virus and Hodgkin´s lymphoma, and a biopsy for confirmation, is always required. Diagnostic imaging tests like CT and MRI are useful. The standard treatment remains holocraneal radiotherapy combined with chemotherapy.
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Kantonsspital St Gallen, Klin Innere Med C, CH-9007 St Gallen, SwitzerlandKantonsspital St Gallen, Klin Innere Med C, CH-9007 St Gallen, Switzerland
Ruhstaller, TW
Amsler, U
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Kantonsspital St Gallen, Klin Innere Med C, CH-9007 St Gallen, SwitzerlandKantonsspital St Gallen, Klin Innere Med C, CH-9007 St Gallen, Switzerland
Amsler, U
Cerny, T
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Kantonsspital St Gallen, Klin Innere Med C, CH-9007 St Gallen, SwitzerlandKantonsspital St Gallen, Klin Innere Med C, CH-9007 St Gallen, Switzerland