Prevalence and burden of pediatric-onset systemic lupus erythematosus

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作者
Sylvia Kamphuis
Earl D. Silverman
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[1] The Hospital for Sick Children,Division of Rheumatology, Department of Pediatrics
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摘要
Pediatric-onset systemic lupus erythematosus (pSLE) is associated with higher disease severity and damage accrual compared with adult-onset SLE. In this Review, the authors describe specific features of pSLE, including epidemiology, disease activity and outcomes, and the effects of the disease on patients' quality of life, bone health and comorbidities.
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页码:538 / 546
页数:8
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