Emerging combinatorial hormone therapies for the treatment of obesity and T2DM

被引：0
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作者：
Sharon A. Sadry
Daniel J. Drucker
机构：
[1] Samuel Lunenfeld Research Institute,Department of Medicine
[2] Mount Sinai Hospital,undefined
来源：
Nature Reviews Endocrinology | 2013年 / 9卷
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摘要：
The success of bariatric surgery, together with emerging data from preclinical studies, illustrates the rationale and feasibility of using two or more agonists for the treatment of obesity and type 2 diabetes mellitus (T2DM). This Review summarizes advances in the science of co-agonist therapy and mechanisms of action for combinations of endocrine hormones that enhance weight loss whilst preserving glucoregulatory efficacy in experimental models of obesity and T2DM.
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页码：425 / 433
页数：8
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