It's all downhill from here

被引：0

作者：

Charles E. Hornsby

Robert S. Paton

机构：

[1] Robert S. Paton and Charles E. Hornsby are in the Chemistry Research Laboratory,

[2] University of Oxford,undefined

[3] Mansfield Road,undefined

[4] Oxford OX1 3TA,undefined

[5] UK,undefined

来源：

Nature Chemistry | 2014年 / 6卷 / 2期

关键词：

D O I：

10.1038/nchem.1852

中图分类号：

学科分类号：

摘要：

High selectivity is essential in the enzymatic biosynthesis of complex natural products. Now, the discovery of multiple sequential bifurcations on the reaction path towards the formation of a diterpenoid shows how dynamics affect selectivity, and suggests how enzymes may steer reactions towards a specific product.

引用

页码：88 / 89

页数：1

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