Virtual methylome dissection facilitated by single-cell analyses

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作者
Liduo Yin
Yanting Luo
Xiguang Xu
Shiyu Wen
Xiaowei Wu
Xuemei Lu
Hehuang Xie
机构
[1] Chinese Academy of Sciences,State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology
[2] University of Chinese Academy of Sciences,Kunming College of Life Science
[3] Chinese Academy of Sciences,Center for Excellence in Animal Evolution and Genetics
[4] Chinese Academy of Sciences,Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics
[5] Virginia Tech,Epigenomics and Computational Biology Lab, Fralin Life Sciences Institute at Virginia Tech
[6] Virginia Tech,Department of Biological Sciences
[7] Virginia Tech,Department of Statistics
[8] Virginia Tech,Department of Biomedical Sciences and Pathobiology, Virginia
[9] University of Chinese Academy of Sciences,Maryland College of Veterinary Medicine
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关键词
DNA methylation; Cellular heterogeneity; Nonnegative matrix factorization; Single-cell methylome;
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