Blocking siglec-10hi tumor-associated macrophages improves anti-tumor immunity and enhances immunotherapy for hepatocellular carcinoma

被引:0
|
作者
Nan Xiao
Xiaodong Zhu
Kangshuai Li
Yifan Chen
Xuefeng Liu
Bin Xu
Ming Lei
Jiejie Xu
Hui-Chuan Sun
机构
[1] Liver Cancer Institute and Zhongshan Hospital,Department of Liver Surgery and Transplantation
[2] Fudan University,Department of Hepatobiliary Surgery
[3] Key Laboratory of Carcinogenesis and Cancer Invasion (Fudan University),Department of Immunology, School of Basic Medical Sciences
[4] Ministry of Education,Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences
[5] Qilu Hospital of Shandong University,undefined
[6] Fudan University,undefined
[7] Fudan University,undefined
关键词
Macrophages; Tumor microenvironment; Hepatocellular carcinoma; Immunotherapy; Immune evasion;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Blocking siglec-10hi tumor-associated macrophages improves anti-tumor immunity and enhances immunotherapy for hepatocellular carcinoma
    Xiao, Nan
    Zhu, Xiaodong
    Li, Kangshuai
    Chen, Yifan
    Liu, Xuefeng
    Xu, Bin
    Lei, Ming
    Xu, Jiejie
    Sun, Hui-Chuan
    EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2021, 10 (01)
  • [2] VSIG4-expressing tumor-associated macrophages impair anti-tumor immunity
    Jung, Keunok
    Jeon, You-kyoung
    Jeong, Dae Hoon
    Byun, Jung Mi
    Bogen, Bjarne
    Choi, Inhak
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 628 : 18 - 24
  • [3] Targeting tumor-associated macrophages in hepatocellular carcinoma: biology, strategy, and immunotherapy
    Zheng, Hongyu
    Peng, Xueqiang
    Yang, Shuo
    Li, Xinyu
    Huang, Mingyao
    Wei, Shibo
    Zhang, Sheng
    He, Guangpeng
    Liu, Jiaxing
    Fan, Qing
    Yang, Liang
    Li, Hangyu
    CELL DEATH DISCOVERY, 2023, 9 (01)
  • [4] Targeting tumor-associated macrophages in hepatocellular carcinoma: biology, strategy, and immunotherapy
    Hongyu Zheng
    Xueqiang Peng
    Shuo Yang
    Xinyu Li
    Mingyao Huang
    Shibo Wei
    Sheng Zhang
    Guangpeng He
    Jiaxing Liu
    Qing Fan
    Liang Yang
    Hangyu Li
    Cell Death Discovery, 9
  • [5] Tumor-associated macrophages and anti-tumor therapies: complex links
    Cristina Belgiovine
    Maurizio D’Incalci
    Paola Allavena
    Roberta Frapolli
    Cellular and Molecular Life Sciences, 2016, 73 : 2411 - 2424
  • [6] Tumor-associated macrophages and anti-tumor therapies: complex links
    Belgiovine, Cristina
    D'Incalci, Maurizio
    Allavena, Paola
    Frapolli, Roberta
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2016, 73 (13) : 2411 - 2424
  • [7] Development of Siglec-9 Blocking Antibody to Enhance Anti-Tumor Immunity
    Choi, Hyeree
    Ho, Michelle
    Adeniji, Opeyemi S.
    Giron, Leila
    Bordoloi, Devivasha
    Kulkarni, Abhijeet J.
    Puchalt, Alfredo Perales
    Abdel-Mohsen, Mohamed
    Muthumani, Kar
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [8] Targeting cGAS-STING pathway for reprogramming tumor-associated macrophages to enhance anti-tumor immunotherapy
    Weiyue Zhang
    Xin Huang
    Biomarker Research, 13 (1)
  • [9] Dectin-2 agonist antibodies reprogram tumor-associated macrophages to drive anti-tumor immunity
    Kenkel, Justin A.
    Ho, Po Y.
    Henning, Karla A.
    Kreder, Cindy L.
    Nolin, Jess L.
    Kongara, Sameera
    Chapin, Steven J.
    Husain, Amreen
    Kowanetz, Marcin
    Engleman, Edgar G.
    Alonso, Michael N.
    Dornan, David
    Ackerman, Shelley E.
    CANCER RESEARCH, 2022, 82 (12)
  • [10] Depletion of tumor-associated macrophages enhances the anti-tumor immunity induced by a Toll-like receptor agonist-conjugated peptide
    Shen, Kuan-Yin
    Song, Ying-Chyi
    Chen, I-Hua
    Chong, Pele
    Liu, Shih-Jen
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2014, 10 (11) : 3241 - 3250