Atomic model of the type III secretion system needle

被引:0
|
作者
Antoine Loquet
Nikolaos G. Sgourakis
Rashmi Gupta
Karin Giller
Dietmar Riedel
Christian Goosmann
Christian Griesinger
Michael Kolbe
David Baker
Stefan Becker
Adam Lange
机构
[1] Max Planck Institute for Biophysical Chemistry,Department of NMR
[2] 37077 Göttingen,based Structural Biology
[3] Germany,Department of Biochemistry
[4] University of Washington,Department of Cellular Microbiology
[5] Max Planck Institute for Infection Biology,undefined
[6] 10117 Berlin,undefined
[7] Germany,undefined
[8] Laboratory for Electron Microscopy,undefined
[9] Max Planck Institute for Biophysical Chemistry,undefined
[10] 37077 Göttingen,undefined
[11] Germany,undefined
[12] Core Facility Microscopy,undefined
[13] Max Planck Institute for Infection Biology,undefined
[14] 10117 Berlin,undefined
[15] Germany,undefined
来源
Nature | 2012年 / 486卷
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摘要
The structure of the needle of the type III secretion system of Salmonella typhimurium, used to inject virulence proteins into host cells during infection, has been resolved by a combination of in vitro needle production, solid-state nuclear magnetic resonance, electron microscopy and Rosetta modelling at atomic resolution.
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页码:276 / 279
页数:3
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