Occupancy by key transcription factors is a more accurate predictor of enhancer activity than histone modifications or chromatin accessibility

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作者
Nergiz Dogan
Weisheng Wu
Christapher S Morrissey
Kuan-Bei Chen
Aaron Stonestrom
Maria Long
Cheryl A Keller
Yong Cheng
Deepti Jain
Axel Visel
Len A Pennacchio
Mitchell J Weiss
Gerd A Blobel
Ross C Hardison
机构
[1] The Pennsylvania State University,Center for Comparative Genomics and Bioinformatics, Department of Biochemistry and Molecular Biology
[2] University of Michigan,Bioinformatics Core, Department of Computational Medicine and Bioinformatics
[3] The Children’s Hospital of Philadelphia,Division of Hematology
[4] Perelman School of Medicine at the University of Pennsylvania,Department of Genetics, Mail Stop
[5] Stanford University,5120
[6] Lawrence Berkeley National Laboratory,Genomics Division
[7] DOE Joint Genome Institute,Department of Hematology
[8] St Jude Children’s Research Hospital,undefined
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Functional genomics; Gene regulation; TAL1; GATA1; Histone modifications; Enhancer assay;
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