Role of lipoprotein-associated phospholipase A2 in atherosclerosis

被引：0
|
作者：
Shahar Lavi
Joerg Herrmann
Ronit Lavi
Joseph P. McConnell
Lilach O. Lerman
Amir Lerman
机构：
[1] Mayo Clinic,Division of Cardiovascular Diseases
来源：
Current Atherosclerosis Reports | 2008年 / 10卷
关键词：
Acute Coronary Syndrome; Stable Coronary Artery Disease; Arterioscler Thromb Vasc Biol; Coronary Endothelial Dysfunction; Stable Coronary Disease;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a biomarker that can be used to assess the risk for cardiovascular disease and events. In addition to being a useful marker of a risk factor, several studies suggest that Lp-PLA2 has a pathophysiologic role in the atherosclerotic disease process. In this article, we review this aspect and its therapeutic implications.
引用
收藏
相关论文
共 50 条
  • [1] Role of Lipoprotein-Associated Phospholipase A2 in Atherosclerosis
    Lavi, Shahar
    Herrmann, Joerg
    Lavi, Ronit
    McConnell, Joseph P.
    Lerman, Lilach O.
    Lerman, Amir
    CURRENT ATHEROSCLEROSIS REPORTS, 2008, 10 (03) : 230 - 235
  • [2] Lipoprotein-associated phospholipase A2 and atherosclerosis
    Wilensky, Robert L.
    Macphee, Colin H.
    CURRENT OPINION IN LIPIDOLOGY, 2009, 20 (05) : 415 - 420
  • [3] The role of lipoprotein-associated phospholipase A2 as a marker for atherosclerosis
    Virani S.S.
    Nambi V.
    Current Atherosclerosis Reports, 2007, 9 (2) : 97 - 103
  • [4] Examining the Role of Lipoprotein-Associated Phospholipase A2 in Atherosclerosis
    Gilpatrick, Timothy Edward
    Tomczak, Jonathan
    Bahnson, Brian J.
    FASEB JOURNAL, 2012, 26
  • [5] New insights into the role of lipoprotein(a)-associated lipoprotein-associated phospholipase A2 in atherosclerosis and cardiovascular disease
    Tsimikas, Sotirios
    Tsironis, Loukas D.
    Tselepis, Alexandros D.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2007, 27 (10) : 2094 - 2099
  • [6] Elevated Lipoprotein-Associated Phospholipase A2 Is Associated With Intracranial Atherosclerosis
    Wang, Yuan
    Liu, Gang
    Song, Haiqing
    Cao, Catherine
    Ji, Xunming
    Cao, Guodong
    FRONTIERS IN NEUROLOGY, 2022, 13
  • [7] Clinical Role of Lipoprotein-Associated Phospholipase A2
    Miklishanskaya, S. V.
    Lyakishev, A. A.
    Kukharchuk, V. V.
    KARDIOLOGIYA, 2013, 53 (03) : 59 - 70
  • [8] The Role of Lipoprotein-Associated Phospholipase A2 as a Marker and Potential Therapeutic Target in Atherosclerosis
    Ralph A. H. Stewart
    Harvey D. White
    Current Atherosclerosis Reports, 2011, 13 : 132 - 137
  • [9] Role of lipoprotein-associated phospholipase A2 in atherosclerosis and its potential as a therapeutic target
    Macphee, CH
    Nelson, J
    Zalewski, A
    CURRENT OPINION IN PHARMACOLOGY, 2006, 6 (02) : 154 - 161
  • [10] The Role of Lipoprotein-Associated Phospholipase A2 as a Marker and Potential Therapeutic Target in Atherosclerosis
    Stewart, Ralph A. H.
    White, Harvey D.
    CURRENT ATHEROSCLEROSIS REPORTS, 2011, 13 (02) : 132 - 137
12345