Malignant Pleural Mesothelioma

被引:0
|
作者
Siva Raja
Sudish C. Murthy
David P. Mason
机构
[1] Cleveland Clinic Foundation,Department of Cardiothoracic Surgery
来源
Current Oncology Reports | 2011年 / 13卷
关键词
Mesothelioma; Multimodality therapy; Extrapleural pneumonectomy; Pleurectomy; Malignant pleural mesothelioma; Lung cancer;
D O I
暂无
中图分类号
学科分类号
摘要
Malignant pleural mesothelioma (MPM) is a relatively rare thoracic malignancy accounting for about 2000–3000 new cases per year. This cancer has been increasing in incidence and is strongly associated with asbestos exposure. Also, it is characterized by insidious growth and clinical presentation at an advanced stage of disease. In the past, the treatment of this disease was limited to marginally effective chemotherapy and morbid surgery. This review explores the clinical presentation of MPM, its diagnostic approach and the relevant and recent studies that define the role of chemotherapy, radiation, and various surgical options. Currently, even with aggressive surgical interventions and multimodality strategies, cure remains elusive, although life prolongation has been achieved. Additionally, promising new therapies and interventions that are currently being studied are introduced in this review.
引用
收藏
页码:259 / 264
页数:5
相关论文
共 50 条
  • [1] Malignant pleural mesothelioma
    Hughes, RS
    [J]. AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2005, 329 (01): : 29 - 44
  • [2] Malignant pleural mesothelioma
    Schouwink, H
    Baas, P
    Rutgers, ETH
    Zoetmulder, FAN
    [J]. EUROPEAN RESPIRATORY JOURNAL, 1999, 13 (03) : 706 - 706
  • [3] MALIGNANT PLEURAL MESOTHELIOMA
    FISHMAN, L
    [J]. JOURNAL OF THE MAINE MEDICAL ASSOCIATION, 1978, 69 (03): : 70 - 71
  • [4] MALIGNANT PLEURAL MESOTHELIOMA
    VAGLINI, M
    BOZZETTI, F
    VIGANOTTI, G
    [J]. TUMORI, 1978, 64 (05) : 529 - 534
  • [5] Malignant pleural mesothelioma
    Baas, P
    Schouwink, H
    Zoetmulder, FAN
    [J]. ANNALS OF ONCOLOGY, 1998, 9 (02) : 139 - 149
  • [6] Malignant pleural mesothelioma
    Chen, Sheree E.
    Pace, Makala B.
    [J]. AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY, 2012, 69 (05) : 377 - 385
  • [7] Malignant Pleural Mesothelioma
    Bois, Melanie C.
    Lee, Hee Eun
    Erickson, Lori A.
    [J]. MAYO CLINIC PROCEEDINGS, 2016, 91 (07) : E103 - E104
  • [8] Malignant pleural mesothelioma
    Pass, HI
    Vogelzang, NJ
    Hahn, S
    Carbone, M
    [J]. CURRENT PROBLEMS IN CANCER, 2004, 28 (03) : 85 - +
  • [9] Malignant Pleural Mesothelioma
    Tsao, Anne S.
    Wistuba, Ignacio
    Roth, Jack A.
    Kindler, Hedy Lee
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (12) : 2081 - 2090
  • [10] Malignant pleural mesothelioma
    Boutin, C
    Schlesser, M
    Frenay, C
    Astoul, P
    [J]. EUROPEAN RESPIRATORY JOURNAL, 1998, 12 (04) : 972 - 981