Analysis of the iron state in ferric and ferrous iron containing pharmaceutical products by Mössbauer spectroscopy

被引:0
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作者
O. B. Oshtrakh
M. I. Milder
V. A. Semionkin
机构
[1] Division of Applied Biophysics,
[2] Faculty of Physical Techniques and Devices for Quality Control,undefined
[3] Ural State Technical University - UPI,undefined
[4] Faculty of Experimental Physics,undefined
[5] Ural State Technical University - UPI,undefined
[6] Faculty of Experimental Physics,undefined
[7] Ural State Technical University - UPI,undefined
关键词
High Spin; Ferrous Iron; Ferrous Sulfate; Iron State; Hyperfine Parameter;
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摘要
An analysis of the iron state in commercial pharmaceuticals containing ferric and ferrous iron compounds, which are used for treatment of iron deficiency, was made by Mössbauer spectroscopy. Small variations of the FeOOH cores of injectable iron-dextran complexes were observed. The presence of ferrous impurity in iron-dextran complexes was found. Characterization of the iron state in vitamins and dietary supplements containing ferrous compounds was made. The presence of ferrous and ferric impurities and iron compounds that were in disagreement with compounds announced by the manufacturer was detected by Mössbauer spectroscopy.
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页码:547 / 553
页数:6
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