High-performance liquid chromatography on silica modified with temperature-responsive polymers

被引:0
|
作者
Y. -X. Song
J. -Q. Wang
Z. -X. Su
D. -Y. Chen
机构
[1] Lanzhou University,Department of Chemistry
[2] Lanzhou Medical College,undefined
来源
Chromatographia | 2001年 / 54卷
关键词
Column liquid chromatography; Temperature-responsive stationary phases; Poly(N-isopropylacrylamide); Selectivity vs temperature;
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中图分类号
学科分类号
摘要
The separation selectivity of temperature-responsive poly(N-isopropylacrylamide)-modified silica as a packing material for high performance liquid chromatography was investigated with steroids, alkaloids, and substituted anilines as solutes. The elution profiles of the solutes depended on the temperature of the column and the methanol content of the mobile phase, indicating that the separation selectivity could be controlled by the column temperature or the mobile phase composition.
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页码:208 / 212
页数:4
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